It is common for people with MS to give up work or reduce working hours, often because the burden of physical disability, cognitive difficulties, fatigue or depression becomes too heavy [1,2].


In the BENEFIT-11 study, 73.4% of patients continued to work compared with 81.3% at baseline. Over 80% of those employed continued to work 20 hours or more per week [3].



The data compare in-line or favorably with other evaluations among patients with MS:

  • A survey of 4,590 German MS patients of working age reported an employment/self-employment rate of 51%. These patients had an average disease duration of 16 years [4].
  • Another review of 1,727 MS patients in New Zealand with an average of 15 years since symptom onset found that more than half (54%) were unemployed [5].
  • In a longitudinal Australian cohort study (N=207), 74% of the patients continued to be employed 10 years after a first episode of central nervous system demyelination [6]. In comparison: BENEFIT-11 reported an employment rate of 73% [7].


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Employment status remained largely stable for the majority of patients in the BENEFIT study [3] and compared favorably with other recent evaluations of MS patients [4-6]


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