It is common for people with MS to give up work or reduce working hours, often because the burden of physical disability, cognitive difficulties, fatigue or depression becomes too heavy [1,2].
In the BENEFIT-11 study, 73.4% of patients continued to work compared with 81.3% at baseline. Over 80% of those employed continued to work 20 hours or more per week .
The data compare in-line or favorably with other evaluations among patients with MS:
- A survey of 4,590 German MS patients of working age reported an employment/self-employment rate of 51%. These patients had an average disease duration of 16 years .
- Another review of 1,727 MS patients in New Zealand with an average of 15 years since symptom onset found that more than half (54%) were unemployed .
- In a longitudinal Australian cohort study (N=207), 74% of the patients continued to be employed 10 years after a first episode of central nervous system demyelination . In comparison: BENEFIT-11 reported an employment rate of 73% .
Employment status remained largely stable for the majority of patients in the BENEFIT study  and compared favorably with other recent evaluations of MS patients [4-6]
- Kobelt G et al. Mult Scler 2017; 23(2S): 4-16. Return to content
- Kobelt G et al. Mult Scler 2019; 25(5): 740-9. Return to content
- Kappos L et al. Neurology 2016; 87(10): 978-87. Return to content
- Flachenecker P et al. Mult Scler 2017; 23(2_suppl): 78-90. Return to content
- Pearson JF et al. Acta Neurol Scand 2017; 136(3): 223-32. Return to content
- Zarghami A et al. Mult Scler. 2022;28(11):1793-1807. Return to content