The MS population is ageing 
In western countries, more than half of MS patients are now 45 years of age or older [2-4]. The rise in age seems to be mainly driven by declining mortality as the incidence of MS appears relatively stable . MS is also more likely to be diagnosed in patients of a higher age today than in years gone by, as demonstrated in a recent population-based study in Norway . The age of MS onset was found to have steadily increased, with a quarter of patients receiving their diagnosis at the age of 50 years or older .
A study from Bavaria, Germany exemplifies the trends in MS prevalence by age (see below) .
Trends in MS prevalence and incidence in people living in Bavaria, Germany
In this study, health administrative data from more than 10 million people living in Bavaria, Germany, were analyzed . From 2006 to 2015, the MS prevalence increased from 171 to 277 per 100,000, while incidence rates remained relatively stable (range 16-18 per 100,000). A substantial increase in prevalence was observed in those between 40 and 60 years of age. In 2015, 60% of the people with MS were at least 45 years of age or older .
MS prevalence per 100,000 in Bavaria, Germany stratified by age groups in 2006 and 2015 
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