Genetic risk of MS
MS patients who are planning to start a family may be concerned about passing down MS to their child . Although MS does not follow Mendelian patterns of inheritance, its incidence and prevalence are higher in family members of affected individuals compared with the general population . According to current understanding, the development of MS is based on complex and individually heterogeneous interactions between genetic and environmental factors . A number of risk and susceptibility genes for MS have been identified , but their precise biological roles remain to be clarified . In Germany, the estimated risk of MS in the general population is 0.1-0.2%. This risk increases depending on the degree of the relationship with someone who has MS (see figure) .
Risk of MS by relationship to someone with MS 
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